Bone Marrow Transplantation
Advanced Therapies Offering New Hope for Hematological Disorders
What is Bone Marrow Transplantation?
Liver transplantation is a life-saving treatment for patients with end-stage liver disease (ESLD) or acute liver failure. Advances in surgical techniques, immunosuppression, and donor management have significantly improved outcomes in liver transplantation. This article reviews the current state of liver transplant surgery and discusses advanced treatment options.
Types of Bone Marrow Transplants
Allogeneic Transplantation
This involves using stem cells from a donor, typically a family member or unrelated individual.
Autologous Transplantation
This involves using the patient's own stem cells, which are collected, stored, and then reinfused after conditioning.
Transplantation Process
Donor Selection
Identifying a suitable donor based on human leukocyte antigen (HLA) matching.
Conditioning Regimen
Administering high-dose chemotherapy and/or radiation to eradicate the patient’s diseased bone marrow.
Stem Cell Harvesting
Collecting stem cells from the donor or patient’s bone marrow or peripheral blood.
Infusion
Infusing the harvested stem cells into the patient’s bloodstream.
Advanced Treatment Options
Haploidentical Transplantation
Using partially matched family donors, increasing donor availability.
Cord Blood Transplantation
Utilizing umbilical cord blood as a source of stem cells, particularly beneficial for patients with limited donor options.
Reduced-Intensity Conditioning
Minimizing regimen-related toxicity, enabling transplantation in older or more fragile patients.
CAR-T Cell Therapy
Genetically modifying T cells to recognize and target cancer cells, showing promise in treating hematological malignancies.
Gene Editing
Utilizing CRISPR/Cas9 and other technologies to modify genes in stem cells, potentially treating genetic disorders.
Benefits and Risks
- Potential Cure
- Improved Survival
- Quality of Life
- Graft-Versus-Host Disease (GVHD)
- Infection
Outcomes & Future Directions
Better Donor Matching
Enhancing HLA typing and donor-recipient matching to reduce the risk of GVHD and improve outcomes.
Developing Novel Conditioning Regimens
Reducing toxicity and improving efficacy to enable transplantation in a broader range of patients.
Expanding CAR-T Cell Therapy
Exploring applications in solid tumors and autoimmune disorders.
Exclusive Offers for Overseas Patients
Exclusive Offers for Overseas Patients
Access premium healthcare in India with exclusive savings on treatments, travel, and wellness packages — only with Grand Medicare.*
How to Find Us
Fill up the Form and Ask Your Queries
Address
25, Anand Bhuvan , T.H. Kataria Marg Near Hinduja Hospital , Mahim Mumbai, Maharashtra 40001
Phone
+ 91 9819204044
bhaskar@grandmedicareindia.com