Liver Transplant Surgery
Advanced Techniques. Better Outcomes. New Hope for Patients with ESLD or Liver Failure.
Introduction
Liver transplantation is a life-saving treatment for patients with end-stage liver disease (ESLD) or acute liver failure. Advances in surgical techniques, immunosuppression, and donor management have significantly improved outcomes in liver transplantation. This article reviews the current state of liver transplant surgery and discusses advanced treatment options.
Liver Transplant Surgery: Step-by-Step
Donor Selection
A portion of the liver is donated by a living individual, offering advantages in terms of timing and availability.
Surgical Technique
A single deceased donor liver is split into two grafts, allowing two recipients to benefit from one donor liver.
Vascular Anastomosis
The surgeon connects the donor liver’s blood vessels to the recipient’s blood vessels.
Biliary Reconstruction
The surgeon connects the donor liver’s bile duct to the recipient’s bile duct.
Hepatectomy
The recipient’s diseased liver is carefully removed to make way for the donor liver.
Implantation
The donor liver is implanted, and blood flow is restored to the graft.
Intraoperative Monitoring
The surgical team closely monitors the recipient’s vital signs and graft function during the procedure.
Post-operative Care
The recipient is closely monitored for complications and graft function in the post-operative period.
Advanced Treatment Options
Living Donor Liver Transplantation
A portion of liver is donated by a living person, improving timing and availability.
Split Liver Transplantation
One donor liver benefits two recipients using specialized splitting techniques.
ABO-Incompatible Transplant
Blood group mismatch handled with advanced immunosuppression.
Auxiliary Liver Transplantation
A donor liver is added alongside the native liver for partial support.
Machine Perfusion
Keeps the liver viable outside the body before transplantation.
Immunosuppression Advances
🧬 Novel immunosuppressive agents: Targeted therapies reducing rejection rates and improving graft survival.
🎯 Personalized immunosuppression: Tailoring regimens to individual patients’ needs and risk profiles.
Outcomes & Future Directions
Xenotransplantation
Transplanting livers from animal donors.
Regenerative medicine
Developing bioengineered livers or liver cells.
Artificial Liver Devices
Creating implantable or extracorporeal devices supporting liver function.
Why Choose Grand Medicare India
- NABH-accredited specialists
- Cutting-edge transplant technology
- 24/7 critical care & ICU monitoring
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